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Yes, it possible in general. Please, take a look at the Modify axis properties example to see different axis/labels formatting in action, and Using of a PaletteProvider or Drag gorizontal treshold to see how parts of the single series can be differently colored. To have a similar tooltip behavior on a series, TooltipModifier can be used.
For more detailed answer, please, specify in the request which particular features you are looking for. Then we could suggest you something or point at some example of implementation.
Hope this helps,
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